Cambridge Healthtech Institute’s 9th Annual
3D Models & NAMs in Drug Development
Physiologically Relevant Non-Animal Testing Methodologies and Their Emerging Applications
September 22, 2025
There is growing pressure to minimize the use of animal models for drug development which has led to innovations in developing in vitro models for drug discovery and testing. Emerging 3D organoids, 3D spheroids, bioprinted tissues, microphysiological systems (MPS), all broadly classified as new approach methodologies (NAMs), are getting better at replicating complex cellular interactions and disease pathology. Now it’s important to know which model is best suited for a specific application, how good is the data, how translatable it is to the clinic, can the findings be replicated using other models, and where the regulatory agencies stand in terms of accepting these findings. Cambridge Healthtech Institute’s symposium on 3D Models and NAMs in Drug Development highlights some of the recent innovations, as well as existing gaps in adopting these predictive models.
Coverage will include, but is not limited to:
- Disease-specific 3D organoids, spheroids, patient-derived induced pluripotent stem cell models
- Using microphysiological systems, organ-on-a-chip and other multi-parametric models
- Finding the right model system for fit-for-purpose use
- How to successfully adopt and adapt in vitro models for decision-making
- Using high-throughput, less complex versus low throughput, more complex models for testing
- Insights from key global stakeholders (regulatory, government institutes, academia, pharma/biotech, consultants, CROs)
The deadline for priority consideration is March 7, 2025.
All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.
Opportunities for Participation: